Departments
06 in vivo
06 in vivo: Preclinical Safety & Efficacy Evaluation
Introduction
Our in vivo department at INVITROVO offers end-to-end preclinical testing solutions designed to evaluate the safety, efficacy, and biological performance of biomedical innovations in live animal models. We provide a critical bridge between early laboratory research and final clinical application by generating reliable, ethically conducted in vivo data. All studies are conducted under the supervision of licensed veterinarians and in vivo research specialists, ensuring full compliance with ethical standards, animal welfare regulations, and international guidelines. With INVITROVO, you can rely on scientifically robust and ethically sound in vivo research that confidently moves your innovations toward clinical translation.
Aim
The strategic aim of the In Vivo Department is to validate translational potential and mitigate risk by providing the definitive data required for clinical transition. We achieve this by focusing on three core objectives:
- To Establish Efficacy and Safety: To rigorously evaluate the safety, efficacy, and biological performance of novel biomedical innovations within physiologically relevant live animal models.
- To Select Optimal Models: To utilize a broad range of carefully selected animal models (including mice, rats, rabbits, dogs, sheep, cows, and horses) that accurately match the scale and complexity of the therapeutic target and regulatory requirements.
- To Ensure Ethical Compliance: To conduct all studies under the supervision of veterinary professionals, ensuring the highest standards of animal welfare, ethical regulation, and scientific integrity are met throughout the research process.
Scope
The operational scope of the 06 in vivo department encompasses comprehensive preclinical support, covering animal model selection, customized disease modeling, full animal care, and longitudinal monitoring. We provide end-to-end support covering:
- Animal Model Management:
- Utilizing a broad range of established animal models to suit project scale and complexity.
- Custom development of models in collaboration with your team to meet specific project goals.
- Disease Model Creation:
- Supporting a wide variety of disease models, including those tailored for wound healing, infections, inflammation, bone regeneration, and cancer.
- Specialized models for cardiovascular, respiratory, and metabolic disorders.
- Full Animal Care and Support:
- Providing professional animal housing and monitoring.
- Delivering specialized support, including post-surgical care, pain management, nutritional support, and routine health checks.
- Longitudinal Monitoring and Analysis:
- Conducting essential long-term assessments, such as imaging, blood sampling, and behavior analysis.
- Ensuring compliance with international guidelines and regulatory needs.
Meet the Experts
Dr. Sepideh Maddah
Dr. Mehran Beikha
