Articular cartilage injuries are difficult to heal due to the avascular and aneural nature of cartilage tissue. Mechanical stimulation plays a crucial role in chondrogenesis, but traditional scaffolds often fail to mimic the bioelectrical cues generated by dynamic joint movement. Piezoelectric materials, which generate electric charges under mechanical stress, offer a smart and non-invasive solution to activate cellular pathways involved in cartilage repair. In this study, a piezoelectric scaffold composed of Zeolite and Hydroxyapatite (HA), termed PiezoCart, is developed to support cartilage regeneration. It utilizes human mesenchymal stem cells (hMSCs) and provides electrical stimulation in response to natural joint motion, thereby promoting chondrogenic differentiation and tissue repair.